Case Reports
Intoxication caused by interaction of chloramphenicol and phenytoin
- PMID: 576989
Item in Clipboard
Case Reports
Intoxication caused by interaction of chloramphenicol and phenytoin
JAMA.
.
Abstract
A patient with a brain tumor and seizures who was receiving maintenance doses of phenytoin was given chloramphenicol on three occasions. Her neurological status was both complicated and obscured by the reoccurrence of phenytoin intoxication. Retrospective drug analysis showed a marked elevation of serum concentrations of phenytoin during each course of chloramphenicol.
Similar articles
-
Interaction of chloramphenicol with phenytoin and phenobarbital. Case report.Clin Pharmacol Ther. 1978 Nov;24(5):571-5. doi: 10.1002/cpt1978245571. Clin Pharmacol Ther. 1978. PMID: 699481
-
Involuntary movements caused by phenytoin intoxication in epileptic patients.J Neurol Neurosurg Psychiatry. 1975 Mar;38(3):225-31. doi: 10.1136/jnnp.38.3.225. J Neurol Neurosurg Psychiatry. 1975. PMID: 239101 Free PMC article.
-
Inhibition of phenytoin metabolism by other drugs used in epilepsy.Int J Clin Pharmacol Biopharm. 1975 Jul;12(1-2):210-6. Int J Clin Pharmacol Biopharm. 1975. PMID: 240782
-
[A case of phenytoin intoxication caused by interaction between phenytoin and capecitabine].Brain Nerve. 2015 Feb;67(2):213-7. doi: 10.11477/mf.1416200115. Brain Nerve. 2015. PMID: 25681367 Review. Japanese.
-
[A successful case of hollow-fiber plasmapheresis for prolonged phenytoin intoxication].Nihon Naika Gakkai Zasshi. 1989 Aug;78(8):1194-8. doi: 10.2169/naika.78.1194. Nihon Naika Gakkai Zasshi. 1989. PMID: 2681476 Review. Japanese. No abstract available.
Cited by
-
Clinical pharmacokinetic considerations in the treatment of increased intracranial pressure.Clin Pharmacokinet. 1987 Jul;13(1):1-25. doi: 10.2165/00003088-198713010-00001. Clin Pharmacokinet. 1987. PMID: 3304768 Review.
-
Pharmacokinetic interactions with antiepileptic drugs.Clin Pharmacokinet. 1982 Jan-Feb;7(1):57-84. doi: 10.2165/00003088-198207010-00004. Clin Pharmacokinet. 1982. PMID: 7042173 Review.
-
Drug interactions with phenytoin.Drugs. 1981 Feb;21(2):120-37. doi: 10.2165/00003495-198121020-00003. Drugs. 1981. PMID: 7009138 Review.
-
Pharmacokinetic drug interactions with phenytoin (Part II).Clin Pharmacokinet. 1990 Feb;18(2):131-50. doi: 10.2165/00003088-199018020-00004. Clin Pharmacokinet. 1990. PMID: 2180613 Review. No abstract available.
-
Clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate.Clin Pharmacokinet. 1984 May-Jun;9(3):222-38. doi: 10.2165/00003088-198409030-00004. Clin Pharmacokinet. 1984. PMID: 6375931 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
