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. 1969 Jan;111(1):59-61.
doi: 10.1042/bj1110059.

The interaction between alpha-2-macroglobulin and cationic aspartate aminotransferase

T R Boyde

The interaction between alpha-2-macroglobulin and cationic aspartate aminotransferase

T R Boyde. Biochem J. 1969 Jan.

Abstract

On starch-gel or polyacrylamide-gel electrophoresis of human serum, a supernumerary zone of aspartate aminotransferase activity may be demonstrated, migrating with the slow alpha(2) protein zone. This appearance is due only to cationic aspartate aminotransferase, bound by alpha(2)-macroglobulin. The binding is strongly potentiated by dilute borate buffers.

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