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. 1969 Feb;35(2):295-303.

The relationship between tremor and change in brain acetylcholine concentration produced by injection of tremorine or oxotremorine in the rat

B Cox, D Potkonjak

The relationship between tremor and change in brain acetylcholine concentration produced by injection of tremorine or oxotremorine in the rat

B Cox et al. Br J Pharmacol. 1969 Feb.

Abstract

1. The relationship between tremor and change in brain acetylcholine concentration after the injection of tremorine or oxotremorine has been investigated in rats.2. Tremorine produced a significant increase in whole brain acetylcholine and in tremor 5 min after injection. After this time tremor subsided but brain acetylcholine continued to increase.3. Oxotremorine produced tremor within 30 sec. This became maximal within 5 min of injection and then declined rapidly. The brain acetylcholine concentration showed a significant increase 5 min after injection and continued to increase until 30 min afterwards.

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References

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