doi: 10.1007/BF00293860.
Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential
- PMID: 577680
- DOI: 10.1007/BF00293860
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Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential
Arch Toxicol.
.
Abstract
The assay of neurotoxic esterase (NTE) in brains taken from dosed hens enables potential neurotoxicity of organophosphate pesticides, plasticers, etc. to be assessed. The original assay [Johnson, M.K. Biochem. J. 114, 711-717 (1969)] has been simplified to eliminate centrifugation and transfer steps and both the selectivity and the sensitivity have been increased. The procedures necessary to obtain stable reagent stocks are described.
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