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. 1977 Jun 18;37(2):113-5.
doi: 10.1007/BF00293860.

Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential

M K Johnson

Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential

M K Johnson. Arch Toxicol. .

Abstract

The assay of neurotoxic esterase (NTE) in brains taken from dosed hens enables potential neurotoxicity of organophosphate pesticides, plasticers, etc. to be assessed. The original assay [Johnson, M.K. Biochem. J. 114, 711-717 (1969)] has been simplified to eliminate centrifugation and transfer steps and both the selectivity and the sensitivity have been increased. The procedures necessary to obtain stable reagent stocks are described.

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References

    1. CRC Crit Rev Toxicol. 1975 Jun;3(3):289-316 - PubMed
    1. Biochem J. 1969 Oct;114(4):711-7 - PubMed
    1. Arch Toxicol. 1975 Dec 18;34(4):259-88 - PubMed

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