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. 1969 May 2;164(3879):574-5.
doi: 10.1126/science.164.3879.574.

Lysergic acid diethylamide: effects on the developing mouse lens

J K Hanaway

Lysergic acid diethylamide: effects on the developing mouse lens

J K Hanaway. Science. .

Abstract

High doses (5 x 10-(6) gram) of LSD-25 given to Swiss-Webster females on gestation days 6, 7, 8, or 9 caused a high incidence of anterior subcapsular lens abnormalities. Accompanying this, the lens epithelium was often hyperplastic, and the lens bow was widened posteriorly in a fashion similar to cataracts induced by x-radiation. Confirmation of this effect of LSD-25 was obtained by a (duplicate) experiment 1 year after the observations reported.

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