[Model building in pharmacokinetics/Part I: General strategy (author's transl)]
[Article in
German]
- PMID: 577856
Item in Clipboard
[Model building in pharmacokinetics/Part I: General strategy (author's transl)]
[Article in
German]
Arzneimittelforschung.
1977.
Abstract
A repetitive cycle: hypothesis-experiment-analysis is typical for construction and evaluation of models in pharmacokinetics. A general strategy is outlined to meet the requirements of correct modelling, proper experimental design, careful experiments, valid parameter estimation and model identification.
Similar articles
-
[Model building in pharmacokinetics/Part IV: Derivation of microconstants in linear compartment models (author's transl)].Arzneimittelforschung. 1977;27(4a):912-28. Arzneimittelforschung. 1977. PMID: 577859 German. No abstract available.
-
[Model building in pharmacokinetics/Part II: Generalized theoretical presentation of complete integration of linear compartment models of optional structure (author's transl)].Arzneimittelforschung. 1977;27(4a):900-4. Arzneimittelforschung. 1977. PMID: 577857 German.
-
[Model building in pharmacokinetics/Part III: Simplified rules for the deduction of analytical solutions for linear compartment models (author's transl)].Arzneimittelforschung. 1977;27(4a):904-11. Arzneimittelforschung. 1977. PMID: 577858 German.
-
Population pharmacokinetics III: design, analysis, and application of population pharmacokinetic Studies.Ann Pharmacother. 2004 Dec;38(12):2136-44. doi: 10.1345/aph.1E260. Epub 2004 Oct 26. Ann Pharmacother. 2004. PMID: 15507495 Review.
-
[Drug concentration-effect correlation].Duodecim. 1999;115(20):2275-83. Duodecim. 1999. PMID: 11973932 Review. Finnish. No abstract available.
Cited by
-
Pharmacokinetics of ampicillin and sulbactam in patients undergoing heart surgery.Antimicrob Agents Chemother. 1991 Sep;35(9):1772-6. doi: 10.1128/AAC.35.9.1772. Antimicrob Agents Chemother. 1991. PMID: 1952846 Free PMC article.