doi: 10.1016/S0006-3495(69)86390-3.
Radiation-induced breaks of DNA in cultured mammalian cells
- PMID: 5780712
- PMCID: PMC1367572
- DOI: 10.1016/S0006-3495(69)86390-3
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Radiation-induced breaks of DNA in cultured mammalian cells
Biophys J.
1969 Mar.
Abstract
Mouse leukemic cells (L5178Y) in suspension culture were irradiated and the extent of single-strand breaks and double-strand cuts of DNA was estimated by sucrose gradient centrifugation. The radiation produced 3.0 single-strand breaks per cell (G(1) stage) per rad and approximately 0.3 double-strand breaks per cell (G(1) stage) per rad.
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