Exopenicillinase synthesis in Staphylococcus aureus
- PMID: 5784217
- PMCID: PMC284868
- DOI: 10.1128/jb.98.2.659-661.1969
Exopenicillinase synthesis in Staphylococcus aureus
Abstract
In Staphylococcus aureus, penicillinase remaining cell-bound (60 to 75% of original total) after treatment with citrate does not become exopenicillinase. Exopenicillinase in these cells appears only under conditions permitting de novo penicillinase synthesis. By use of (14)C-labeled cells, it was shown that exopenicillinase consists of newly synthesized molecules which have not equilibrated with preformed membrane-bound enzyme.
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