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. 1969 May;17(5):695-700.
doi: 10.1128/am.17.5.695-700.1969.

Effect of chloral hydrate on methane and propionic acid in the rumen

Effect of chloral hydrate on methane and propionic acid in the rumen

C J Van Nevel et al. Appl Microbiol. 1969 May.

Abstract

Methane production from pyruvate by mixed rumen bacteria in vitro was nearly totally inhibited by chloral hydrate (0.1 mumole/ml of incubation fluid). This effect was accompanied by an accumulation of gaseous hydrogen and an increase in propionic acid production. Infusion of chloral hydrate (4 g/day) into the rumen of a sheep produced the same effects. Evidence is presented for a direct toxic effect of chloral hydrate upon methane bacteria. Results are discussed in terms of fermentation balances.

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References

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