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. 1969 May;3(5):490-7.
doi: 10.1128/JVI.3.5.490-497.1969.

Changes in nuclear basic proteins during pseudorabies virus infection

J G Stevens, G J Kado-Boll, C B Haven

Changes in nuclear basic proteins during pseudorabies virus infection

J G Stevens et al. J Virol. 1969 May.

Abstract

As a preliminary study to investigation of the possible role played by basic proteins in the genetic regulation of virus-infected cells, acid-extractable proteins synthesized during pseudorabies virus infection were investigated. The synthesis of histones was found to decrease in a gradual manner, and arrest was complete by 6 hr after infection. Five virus-induced acid-extractable proteins appeared in nuclei of infected cells after 4 hr of infection. Four of these proteins were virus structural proteins; one was not. All these proteins contained tryptophan and, therefore, were not "classic" histones.

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References

    1. Science. 1968 Jan 5;159(3810):47-56 - PubMed
    1. J Bacteriol. 1965 May;89:1328-34 - PubMed
    1. Biochem Biophys Res Commun. 1967 Sep 7;28(5):815-20 - PubMed
    1. J Virol. 1968 Jan;2(1):48-55 - PubMed
    1. Biochemistry. 1968 Feb;7(2):575-85 - PubMed