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. 1977;27(96):1836-44.

[Polymorphisms and deficient drug metabolism as triggers of toxic reactions (author's transl)]

[Article in German]
H J Dengler, M Eichelbaum
  • PMID: 579150

[Polymorphisms and deficient drug metabolism as triggers of toxic reactions (author's transl)]

[Article in German]
H J Dengler et al. Arzneimittelforschung. 1977.

Abstract

The influences of polymorphisms and pharmacokinetic defects of drug metabolism as causes of toxic drug reactions are presented. The different mechanisms of toxic side effects mediated by alterations of the metabolism and excretion of drugs are discussed.

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