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. 1975;5(5):273-92.
doi: 10.1159/000149924.

Reverse transciptase activity associated with R-type virus-like particles of SV40-transformed hamster cells (TSV5 clone 2)

J M Rossignol, M Kress, A M de Recondo

Reverse transciptase activity associated with R-type virus-like particles of SV40-transformed hamster cells (TSV5 clone 2)

J M Rossignol et al. Intervirology. 1975.

Abstract

A line of hamster cells transformed by SV40 (TSV5 clone 2) contains different DNA polymerase activities. One of them has the same template specificity as viral reverse transcriptases. Partial isolation of R-type virus-like particles from TSV5 clone 2 shows that a reverse transcriptase activity is associated with these RNA viruses. This reverse transcriptase was partially purified and its biochemical properties are described.

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