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Comparative Study
. 1977 Aug 31;38(2):438-46.

The activation of plasma factor XIII with the snake venom enzymes ancrod and batroxobin marajoensis

M Walter, D Nyman, V Krajnc, F Duckert
  • PMID: 579487
Comparative Study

The activation of plasma factor XIII with the snake venom enzymes ancrod and batroxobin marajoensis

M Walter et al. Thromb Haemost. .

Abstract

The snake venom enzymes Ancrod and Batroxobin marajoensis are able to activate human plasma factor XIII as shown by the formation of the gamma-dimers. The concentration of gamma-dimers increases with the concentration of the activating enzymes. Factor XIII activated by Ancrod or Batroxobin marajoensis is, however, unable to catalyse the incorporation of the amine dansyl-cadaverine into casein. The partially activated factor XIII is therefore not demonstrable by means of the artificial test system. This factor XIII loses little activity and remains activable by thrombin.

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