Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1969 Aug;54(2):178-87.
doi: 10.1085/jgp.54.2.178.

A fixed charge model of the transverse tubular system of frog sartorius

S I Rapoport

A fixed charge model of the transverse tubular system of frog sartorius

S I Rapoport. J Gen Physiol. 1969 Aug.

Abstract

Volume changes of the transverse tubular system (T system) of frog sartorius in different solutions can be explained by a model which assumes fixed negative charges in the T system lumen, an open T system mouth, and a Donnan equilibrium between the T system and external solution. The T system volume is regulated by the osmotic pressure difference between the lumen and external solution, as well as by constraining forces whose nature is as yet unclear. The decreased swelling tendency produced by hypotonic solutions and increased tendency produced by some hypertonic solutions are ascribed to changes in the pressure constraint from the sarcoplasm. Fixed charge concentration was estimated tentatively from swelling and resistivity data to be between 0.1 and 0.4 M.

PubMed Disclaimer

References

    1. J Physiol. 1966 Jul;185(1):224-38 - PubMed
    1. J Gen Physiol. 1967 Nov;50(10):2437-58 - PubMed
    1. J Cell Biol. 1969 Jul;42(1):1-45 - PubMed
    1. J Gen Physiol. 1969 Aug;54(2):166-77 - PubMed
    1. J Physiol. 1960 Sep;153:370-85 - PubMed