[The effect of tramadol, a new analgesic, on respiration and cardiovascular function (author's transl)]
[Article in
German]
- PMID: 580215
Item in Clipboard
[The effect of tramadol, a new analgesic, on respiration and cardiovascular function (author's transl)]
[Article in
German]
Arzneimittelforschung.
1978.
Abstract
1. The effect of 1-(m-methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal), a new i.v. administered analgesic, on respiration and cardiovascular function was investigated in 15 patients in a clinic of general surgery. 2. Blood gas analysis revealed that tramadol, unlike morphine-like analgesics, does not depress respiration. 3. The drug did not affect blood pressure, and the observed slight increase in heart rate was transient and statistically not significant.
Similar articles
-
[General pharmacological studies on tramadol, a potent analgetic agent (author's transl)].Arzneimittelforschung. 1978;28(1a):135-51. Arzneimittelforschung. 1978. PMID: 305247 German.
-
[Algo-pupillometric investigation of the analgesic effect of tramadol (author's transl)].Arzneimittelforschung. 1978;28(1a):176-8. Arzneimittelforschung. 1978. PMID: 580212 German.
-
[The effect of tramadol and other analgesics on the pain threshold in human dental pulp (author's transl)].Arzneimittelforschung. 1978;28(1a):181-3. Arzneimittelforschung. 1978. PMID: 580214 Clinical Trial. German.
-
[The effect of tramadol in an open clinical trial (author's transl)].Arzneimittelforschung. 1978;28(1a):209-12. Arzneimittelforschung. 1978. PMID: 343790 Clinical Trial. German.
-
Influence of anaesthesia and analgesia on the control of breathing.Br J Anaesth. 2003 Jul;91(1):40-9. doi: 10.1093/bja/aeg150. Br J Anaesth. 2003. PMID: 12821564 Review. No abstract available.
Cited by
-
Effects of the central analgesic tramadol and its main metabolite, O-desmethyltramadol, on rat locus coeruleus neurones.Br J Pharmacol. 1993 Sep;110(1):169-76. doi: 10.1111/j.1476-5381.1993.tb13788.x. Br J Pharmacol. 1993. PMID: 8220877 Free PMC article.
-
A comparison of the antinociceptive effects of imipramine, tramadol and anpirtoline.Br J Clin Pharmacol. 1994 Apr;37(4):325-33. doi: 10.1111/j.1365-2125.1994.tb04285.x. Br J Clin Pharmacol. 1994. PMID: 8018453 Free PMC article. Clinical Trial.
-
Tramadol for the management of acute pain.Drugs. 1994;47 Suppl 1:19-32. doi: 10.2165/00003495-199400471-00005. Drugs. 1994. PMID: 7517822 Review.
-
Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states.Drugs. 1993 Aug;46(2):313-40. doi: 10.2165/00003495-199346020-00008. Drugs. 1993. PMID: 7691519 Review.
-
[Systemic clonidine versus opioids in postoperative analgesia-A randomized double-blind study.].Schmerz. 1992 Sep;6(3):182-91. doi: 10.1007/BF02528598. Schmerz. 1992. PMID: 18415602 German.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources