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. 1969 Sep 5;165(3897):1025-7.
doi: 10.1126/science.165.3897.1025.

Erythropoiesis in the dog: the periodic nature of the steady state

Erythropoiesis in the dog: the periodic nature of the steady state

A Morley et al. Science. .

Abstract

In at least six of 11 normal dogs serial measurement of reticulocyte counts showed oscillation with a period of approximately 14 days. The phase of oscillation could be altered by bleeding followed by retransfusion. The observations suggest that canine erythropoiesis is an example of a physiological rhythm which has its origin in homeostatic control.

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