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. 1969 Oct 10;166(3902):239-40.
doi: 10.1126/science.166.3902.239.

Allergenic component of a liverwort: a sesquiterpene lactone

H Knoche, G Ourisson, G W Perold, J Foussereau, J Maleville

Allergenic component of a liverwort: a sesquiterpene lactone

H Knoche et al. Science. .

Abstract

Frullania spp. (Hepaticae, Jungermanniales) are agents of allergies. Extraction and fractionation of Frullania tamarisci has given, as the only allergenic component isolated, a levorotatory crystalline sutbstance, the structure of which is demonstrated. It is a sesquiterpene lactone. The racemic (+/-) form is isolated from a mixed sample of Frullania tamarisci and Frullania dilatata; the dextrorotatory form, from Frullania dilatata. The observed allergenic properties are shared by some other-sesquiterpene lactones.

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