Late onset chronic mucocutaneous candidiasis with lymphoma and specific serum inhibitory factor
- PMID: 581657
- DOI: 10.1002/1097-0142(197901)43:1<101::aid-cncr2820430116>3.0.co;2-6
Late onset chronic mucocutaneous candidiasis with lymphoma and specific serum inhibitory factor
Abstract
A patient with late onset chronic mucocutaneous candidiasis developed lymphocytic lymphoma. A specific inhibitor of in vitro lymphoproliferative responses to candidal antigen was detected in her serum which persisted following clinical remission of candidiasis after combined amphotericin-B and 5-Fluorocystosine therapy. It is unclear whether the combined therapy was exclusively anticandidal, nonspecific immunostimulant or cytotoxic affecting the underlying incipient lymphoma.