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. 1969 Oct;4(4):496-504.
doi: 10.1128/JVI.4.4.496-504.1969.

Morphogenesis of Venezuelan equine encephalomyelitis virus

Morphogenesis of Venezuelan equine encephalomyelitis virus

A F Bykovsky et al. J Virol. 1969 Oct.

Abstract

Morphogenesis of Venezuelan equine encephalomyelitis virus was studied by means of electron microscopy. Virus-specific structures (factories, viroplasts) were found at early stages of infection; these structures were composed of fibrillar and cylindrical formations, aggregates of ribosomes, and viral nucleoids. The latter emerged from fibrillar and cylindrical structures. Aggregates of viral nucleoids were found in the cytoplasm and occasionally in the nuclei of virus-infected cells. Viral envelopes and mature virions were formed on the cell membranes and on the membranes of intracellular vacuoles. Anomalous forms of virions (both polygenomic and oligogenomic) were observed.

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References

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