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. 1976 Jun 5;1(7971):1217-9.
doi: 10.1016/s0140-6736(76)92164-4.

Pathogenesis of essential hypertension

Pathogenesis of essential hypertension

J J Brown et al. Lancet. .

Abstract

It is proposed that essential hypertension is an exaggeration of the tendency for blood-pressure to rise with age, that it results from a repeated sequence in which a small rise in pressure, possibly resulting from an autonomic nervous overactivity, produces changes in the kidney which maintain the rise of pressure and become the basis for a further rise.

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