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. 1965 Sep 3;149(3688):1102-3.
doi: 10.1126/science.149.3688.1102.

Protein synthesis by ribosomes from heart muscle: effect of insulin and diabetes

O R Rampersad, I G Wool

Protein synthesis by ribosomes from heart muscle: effect of insulin and diabetes

O R Rampersad et al. Science. .

Abstract

Incorporation of phenylalanine into protein by ribosomes from the heart muscle of rats is decreased when the ribosomes are from alloxan-diabetic animals. Protein synthesis is increased when the ribosomes are obtained from nondiabetic animals I hour after treatment with insulin. The change due to insulin appears to be an alteration in the function of the ribosome.

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