[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)]
[Article in
German]
- PMID: 583234
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[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)]
[Article in
German]
Arzneimittelforschung.
1979.
Abstract
Racemic thalidomide is chromatographically separated on optically active polyamide giving both enantiomers. After i.p. administration only the S-(-)-enantiomer is teratogenic on SWS mice and Natal rats.
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