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. 1979;29(10):1640-2.

[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)]

[Article in German]
G Blaschke, H P Kraft, K Fickentscher, F Köhler
  • PMID: 583234

[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)]

[Article in German]
G Blaschke et al. Arzneimittelforschung. 1979.

Abstract

Racemic thalidomide is chromatographically separated on optically active polyamide giving both enantiomers. After i.p. administration only the S-(-)-enantiomer is teratogenic on SWS mice and Natal rats.

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