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. 1965 Dec 17;150(3703):1601-2.
doi: 10.1126/science.150.3703.1601.

X-linked 6-phosphogluconate dehydrogenase in drosophila: subunit associations

H H Kazazian Jr, W J Young, B Childs

X-linked 6-phosphogluconate dehydrogenase in drosophila: subunit associations

H H Kazazian Jr et al. Science. .

Abstract

6-Phosphogluconate dehydrogenase (PGD) subunits have been dissociated and reassociated in vitro. The intermediate PGD of the heterozygous phenotype is reproduced by reassociation in vitro of subunits derived from the two types of PGD from homozygous flies. This result has a bearingon gene action in the diploid organism and on the mechanism of dosage compensation in Drosophila melanogaster.

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