Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1965 Dec;27(3):519-29.
doi: 10.1083/jcb.27.3.519.

The fine structure of the nuclei of Tetrahymena pyriformis throughout the cell cycle

C J Flickinger

The fine structure of the nuclei of Tetrahymena pyriformis throughout the cell cycle

C J Flickinger. J Cell Biol. 1965 Dec.

Abstract

The fine structure of the nuclei of logarithmically growing Tetrahymena pyriformis, strain HSM, was studied at 30-minute intervals throughout the cell cycle. Organisms were selected at similar stages of cytokinesis by means of a braking pipette, incubated, fixed in OsO(4), and embedded in agar to facilitate subsequent preparation for electron microscopy. Aggregates of micronuclear chromatin underwent a decrease in density and number with a concomitant increase in size throughout interphase. There were no impressive changes in macronuclear morphology. It was found possible to estimate a cell's progress through interphase by observation of micronuclear morphology, but attempts to correlate changes in fine structure with periods of DNA synthesis were unsuccessful.

PubMed Disclaimer

References

    1. Exp Cell Res. 1959 Feb;16(2):279-84 - PubMed
    1. Exp Cell Res. 1959 Aug;18:150-66 - PubMed
    1. J Cell Biol. 1962 Mar;12:515-31 - PubMed
    1. J Protozool. 1962 May;9:122-31 - PubMed
    1. J Cell Biol. 1963 Apr;17:208-12 - PubMed