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. 1976 May;3(5):480-5.
doi: 10.1128/jcm.3.5.480-485.1976.

Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III

Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III

H W Wilkinson et al. J Clin Microbiol. 1976 May.

Abstract

The object of this study was to develop a test that would measure antibodies directed against group B streptococcal types Ia, Ib, Ic, II, and III. The type-specific carbohydrate antigens were purified, labeled with 125I, and used to develop a radioimmunoassay. This procedure should be particularly useful in testing human sera for group B type-specific antibodies, since it requires very small quantities of antigens and measures primary type antigen-antibody interactions.

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