Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III
- PMID: 58870
- PMCID: PMC274335
- DOI: 10.1128/jcm.3.5.480-485.1976
Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III
Abstract
The object of this study was to develop a test that would measure antibodies directed against group B streptococcal types Ia, Ib, Ic, II, and III. The type-specific carbohydrate antigens were purified, labeled with 125I, and used to develop a radioimmunoassay. This procedure should be particularly useful in testing human sera for group B type-specific antibodies, since it requires very small quantities of antigens and measures primary type antigen-antibody interactions.
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