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. 1965 Sep 24;149(3691):1504-6.
doi: 10.1126/science.149.3691.1504.

Actinomycin D: inhibition of protein synthesis unrelated to effect on template RNA synthesis

Actinomycin D: inhibition of protein synthesis unrelated to effect on template RNA synthesis

G R Honig et al. Science. .

Abstract

Incubation of sarcoma-37 ascites cells in vitro with actinomycin D resulted in inhibition of synthesis of nuclear and cytoplasmic proteins. The overall inhibition could be prevented or relieved by glucose; it is thus unrelated to breakdown of template RNA.

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