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. 1977 Sep;29(3):464-7.

Enhancement of human lymphocyte responses to phytomitogens in vitro by incubation at elevated temperatures

R B Ashman, A J Nahmias

Enhancement of human lymphocyte responses to phytomitogens in vitro by incubation at elevated temperatures

R B Ashman et al. Clin Exp Immunol. 1977 Sep.

Abstract

Incubation of human lymphocytes with PHA or Con A at 39 degrees C for 3 days caused a consistent, statistically significant, increase in [3H]thymidine uptake, compared with cultures incubated at 37 degrees C. The responses were also significantly increased after 2 days of incubation, suggesting that hyperthermia not only enhanced, but also caused an earlier onset of the mitogen response.

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References

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