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. 1966 Apr 1;152(3718):85-7.
doi: 10.1126/science.152.3718.85.

Lithium's failure to replace sodium in mammalian sympathetic ganglia

A J Pappano, R L Volle

Lithium's failure to replace sodium in mammalian sympathetic ganglia

A J Pappano et al. Science. .

Abstract

Ganglionic responses to electrical stimulation, acetylcholine, and potassium ions were studied in superior cervical ganglia of. cats perfused with media containing lithium chloride instead of sodium chloride. In lithium-Locke, ganglionic transmission and depolarization evoked by acetylcholine were blocked completely but reversibly, while the depolarization produced by potassium ions was unaltered.

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