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. 1977 Nov;30(11):965-8.
doi: 10.7164/antibiotics.30.965.

Synthesis of a 125I-labelled derivative of the antibiotic griseofulvin

Free article

Synthesis of a 125I-labelled derivative of the antibiotic griseofulvin

P Lecointe et al. J Antibiot (Tokyo). 1977 Nov.
Free article

Abstract

A derivative of griseofulvin has been synthesised, in which the 2'-O-methyl group is replaced by a 2'-(2-iodoethoxy), 125I-labelled group. This derivative is at least as potent as griseofulvin itself, when assayed for inhibition of growth on the Myxomycete Physarum polycephalum.

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