N-cyclohexyl linoleamide: metabolism and cholesterol-lowering effect in rats
- PMID: 5918714
- DOI: 10.1126/science.153.3741.1267
N-cyclohexyl linoleamide: metabolism and cholesterol-lowering effect in rats
Abstract
More than half of orally administered N-cyclohexyl linoleamide-car-boxyl-C(14) yl-CI was recovered from feces of rats, and 30 to 50 percent of the absorbed carbon-14 activity was excreted in urine. N-Cyclohexyl linoleamide had an inhibitory eflect on the absorption of cholesterol from the thoracic duct and caused a decrease in the deposition of cholesterol in the livers of rats that had been fed cholesterol.
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