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. 1966 Dec 2;154(3753):1202-5.
doi: 10.1126/science.154.3753.1202.

Segregation of sister chromatids in mammalian cells

K G Lark, R A Consigli, H C Minocha

Segregation of sister chromatids in mammalian cells

K G Lark et al. Science. .

Abstract

Segregation of sister chromatids in embryonic mouse cells in primary tissue culture is not random. In mitosis those chromatids replicated on a DNA template synthesized during the preceding division cycle are separated from those constructed on a template synthesized two division cycles previously. Segregation in cells of the Chinese hamster follows a similar, but less pronounced, pattern.

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