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. 1966 Dec 2;154(3753):1205-6.
doi: 10.1126/science.154.3753.1205.

Rapid and marked inhibition of rat-liver RNA polymerase by aflatoxin B-1

H V Gelboin, J S Wortham, R G Wilson, M Friedman, G N Wogan

Rapid and marked inhibition of rat-liver RNA polymerase by aflatoxin B-1

H V Gelboin et al. Science. .

Abstract

From 15 minutes to 2 hours after the administration of aflatoxin B(1) invivo there is a 35-to 70-percent inhibition of DNA-directed RNA synthesis. The inhibition was reversed 12 and 24 hours later.

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