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. 1966 Dec 1;124(6):1083-8.
doi: 10.1084/jem.124.6.1083.

Studies of PPLO infection. 3. Electron microscopic study of brain lesions caused by Mycoplasma neurolyticum toxin

F Aleu, L Thomas

Studies of PPLO infection. 3. Electron microscopic study of brain lesions caused by Mycoplasma neurolyticum toxin

F Aleu et al. J Exp Med. .

Abstract

The ultrastructure of the experimental encephalopathy caused by Mycoplasma neurolyticum toxin has been studied. The primary changes are (a) massive distention of astrocytes by fluid, associated with degenerative changes in these cells, (b) mechanical displacement and compression of myelinated axons by swollen astrocytic processes, (c) the appearance of free, extracellular fluid in the white matter, and (d) early primary myelin degeneration without damage to axons.

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References

    1. J Exp Med. 1966 Dec 1;124(6):1067-82 - PubMed
    1. Brain. 1960 Dec;83:519-64 - PubMed

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