[Immobilisation hypercalcaemia (author's transl)]
- PMID: 593868
[Immobilisation hypercalcaemia (author's transl)]
Abstract
Hypercalcaemia would seem to be rare during immobilisation, whilst osteoporosis and hypercalciuria are constant. In fact, it often goes unnoticed. The case presented here confirms its predominance in the adolescent male. The reason for immobilisation seems to be irrelevant. The clinical symptoms are very variable: polydipsia, nausea, headache, apathy, anorexia. Blood calcium levels are raised, up to 14 mg%. This hypercalcaemia is due to very marked bone loss in adolescents, secondary to hyper-resorption and a temporary stoppage in osseous formation. The differential diagnosis from primary hyperparathyroidism is sometimes difficult but is aided by laboratory and histological findings. The essential is to consider the possibility of immobilisation hypercalcaemia in the presence of any suggestive symptoms in an immobilised adolescent. Treatment includes a return to weight bearing, adequate water intake and the administration of phosphorus, calcitonin, furosemide, and corticosteroids.
Similar articles
-
Immobilization hypercalcemia following spinal cord injury.Arch Phys Med Rehabil. 1986 Jan;67(1):41-4. Arch Phys Med Rehabil. 1986. PMID: 2935120
-
[Immobilisation hypercalcaemia. 1 case (author's transl)].Nouv Presse Med. 1978 Feb 11;7(6):453-5. Nouv Presse Med. 1978. PMID: 634783 French.
-
Immobilization hypercalcemia in spinal cord injury.Arch Phys Med Rehabil. 1977 Jan;58(1):16-24. Arch Phys Med Rehabil. 1977. PMID: 831659
-
Effects of clodronate on immobilization bone loss.Bone. 1987;8 Suppl 1:S63-8. Bone. 1987. PMID: 2961357 Review.
-
Mechanisms of osteoporosis in spinal cord injury.Clin Endocrinol (Oxf). 2006 Nov;65(5):555-65. doi: 10.1111/j.1365-2265.2006.02683.x. Clin Endocrinol (Oxf). 2006. PMID: 17054455 Review.
Cited by
-
Effects of disodium dichloromethylene diphosphonate on bone loss in paraplegic patients.J Clin Invest. 1981 Oct;68(4):1086-92. doi: 10.1172/jci110331. J Clin Invest. 1981. PMID: 6457060 Free PMC article. Clinical Trial.
-
The effect of short-term calcitonin administration on biochemical bone markers in patients with acute immobilization following hip fracture.Osteoporos Int. 1993 Dec;3(6):337-40. doi: 10.1007/BF01637320. Osteoporos Int. 1993. PMID: 8292845 Clinical Trial.
-
Immobilization osteoporosis: a review.Clin Rheumatol. 1989 Jun;8 Suppl 2:95-103. doi: 10.1007/BF02207242. Clin Rheumatol. 1989. PMID: 2667875 Review.
-
Progressive hypercalcemia during continuous arterio-venous ultrafiltration (SCUF).Intensive Care Med. 1992;18(5):312-4. doi: 10.1007/BF01706482. Intensive Care Med. 1992. PMID: 1527265
-
Aminohydroxypropylidene bisphosphonate (AHPrBP) treatment of severe immobilization hypercalcaemia in a young patient.Clin Rheumatol. 1991 Sep;10(3):328-32. doi: 10.1007/BF02208702. Clin Rheumatol. 1991. PMID: 1790647