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. 1966 Jul 8;153(3732):185-8.
doi: 10.1126/science.153.3732.185.

Lipid films as transducers for detection of antigen-antibody and enzyme-substrate reactions

Lipid films as transducers for detection of antigen-antibody and enzyme-substrate reactions

J Del Castillo et al. Science. .

Abstract

The transverse electrical impedance of thin lipid films separating two aqueous saline solutions containing a small concentration of antibodies or enzymes decreases markedly and reversibly after immunological and enzymatic reactions involving such protein molecules, which presumably are adsorbed to the lipid-water interface.

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