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. 1977 Sep 15;166(3):631-4.
doi: 10.1042/bj1660631.

The effects of inhibition of fatty acid oxidation in suckling newborn rats

J P Pégorier, P Ferré, J Girard

The effects of inhibition of fatty acid oxidation in suckling newborn rats

J P Pégorier et al. Biochem J. .

Abstract

Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential to support gluconeogenesis and to maintain normal blood [glucose] in suckling newborn rats.

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