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. 1977 Sep 15;166(3):639-42.
doi: 10.1042/bj1660639.

The effects of acute ethanol feeding and of chronic benfluorex administration on the activities of some enzymes of glycerolipid synthesis in rat liver and adipose tissue

P H Pritchard, M Bowley, S L Burditt, J Cooling, H P Glenny, N Lawson, R G Sturton, D N Brindley

The effects of acute ethanol feeding and of chronic benfluorex administration on the activities of some enzymes of glycerolipid synthesis in rat liver and adipose tissue

P H Pritchard et al. Biochem J. .

Abstract

Rats were treated for 5 days with benfluorex [1-(3-trifluoromethylphenyl)-2-[N-(2-benzoyloxyethyl)amino]propane] or with suspending medium (controls). They were then intubated with an acute intoxicating dose of ethanol or with glucose of equivalent energy content. Treatment of the control rats with ethanol specifically increases the hepatic activity of the soluble phosphatidate phosphohydrolase by about 5-fold in 6 h. The equivalent increase for the benfluorex-treated rats were about 2-fold. The results are discussed in relation to the effects of ethanol and benfluorex on glycerolipid synthesis.

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References

    1. J Lipid Res. 1965 Apr;6:269-77 - PubMed
    1. Proc Soc Exp Biol Med. 1963 Aug-Sep;113:814-7 - PubMed
    1. J Clin Invest. 1961 Feb;40:394-9 - PubMed
    1. J Lipid Res. 1973 May;14(3):337-43 - PubMed
    1. Atherosclerosis. 1976 Jan-Feb;23(1):63-72 - PubMed