Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1977 Dec 23;39(3):353-7.
doi: 10.1007/BF00295431.

'Gd(-) Hôtel Dieu': a new G-6PD variant with chronic hemolysis in a Negro patient from Senegal

A Kahn, C Dao, D Cottreau, G Bilski-Pasquier
Case Reports

'Gd(-) Hôtel Dieu': a new G-6PD variant with chronic hemolysis in a Negro patient from Senegal

A Kahn et al. Hum Genet. .

Abstract

A G-6PD deficiency was detected in a Negro patient from Senegal suffering from congenital nonspherocytic hemolytic anemia. The main characteristics of this variant were: profound defect of G-6PD activity in the red cells, decreased immunologic specific activity, fast electrophoretic mobility, decreased Km-G-6P and normal Km-NADP+, normal inhibition by ATP and NADPH, slightly increased utilization of the substrate analogues, slightly biphasic pH curve, high heat lability, subnormal activation energy. The characteristics of this variant being unique, it was called 'G-6PD Hôtel Dieu.'

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Science. 1973 Feb 9;179(4073):532-7 - PubMed
    1. Nouv Rev Fr Hematol. 1971 Sep-Oct;11(5):741-58 - PubMed
    1. Ann Hum Genet. 1973 Oct;37(2):151-5 - PubMed
    1. Hum Genet. 1976 May 19;32(2):171-80 - PubMed
    1. Humangenetik. 1974;25(2):101-9 - PubMed

Publication types

Substances

LinkOut - more resources