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. 1977 Dec;15(12):560-2.

Pharmacokinetic aspects of digoxin in patients with terminal renal failure III. Effect of heparin

W J van der Vijgh, P L Oe
  • PMID: 598950

Pharmacokinetic aspects of digoxin in patients with terminal renal failure III. Effect of heparin

W J van der Vijgh et al. Int J Clin Pharmacol Biopharm. 1977 Dec.

Abstract

The effect of an i.v. injection of 25 mg heparin on the plasma digoxin level was studied in ten patients on chronic intermittent hemodialysis. Six patients did not show a significant change in the plasma digoxin level of more than 0.1 ng/ml. An increase up to 0.4 ng/ml was observed in four patients. The consequences with regard to digoxin assay and clinical effects are discussed.

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