[Identification of several chromosome aberrations in man by the fluorescent method using quinacrine yprite]
[Article in
Russian]
- PMID: 59989
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[Identification of several chromosome aberrations in man by the fluorescent method using quinacrine yprite]
[Article in
Russian]
Tsitologiia.
1976 Feb.
Abstract
The applications of the fluorescent staining of chromosomes with quinacrine mustard allowed to identify a dicentric Y-chromosome in two patients with defected external gynaetalies: a boy of 15 years old and a girl of 2 years old. Both the patients had mosaicism of sex chromosomes: 45, x/46, x dic (Y). The dicentric Y-chromosome, resembling chromosome, 16, had bright luminescence of the thelomeric regions characteristic of the normal Y-chromosome. Besides, a balanced autosomic translocation t (1, 14) (q 31, q 3) was found in the girl identified also with quinacrine mustard fluorescent staining.
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