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Comparative Study
. 1977 Dec;4(12):4425-37.
doi: 10.1093/nar/4.12.4425.

The evolution of repetitive DNA sequences in sea urchins

M M Harpold, S P Craig
Free PMC article
Comparative Study

The evolution of repetitive DNA sequences in sea urchins

M M Harpold et al. Nucleic Acids Res. 1977 Dec.
Free PMC article

Abstract

Molecular hybridization of nuclear DNAs has been employed to study the evolution of the repetitive DNA sequences in four species of sea urchin. The data show that relative to S. purpuratus there has been approximately 0.1% sequence divergence per million years in the repetitive DNA sequences of S. droebachiensis, S. franciscanus, and L. pictus. These results confirm that repetitive DNA sequences are strongly conserved during evolution. However, comparison of the extent of base pair mismatch in the repetitive DNA heteroduplexes formed at Cot 20 with those formed at Cot 200 during the hybridization of S. purpuratus and L. pictus DNAs reveals that highly repetitive sequences of sea urchins may diverge more rapidly than do the more moderately repetitive sequences.

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