Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Aug 17;57(2):165-9.
doi: 10.1007/BF00292914.

Negative silver staining in A-T and satellite DNA-rich regions of human chromosomes

W M Howell, T E Denton

Negative silver staining in A-T and satellite DNA-rich regions of human chromosomes

W M Howell et al. Chromosoma. .

Abstract

Human metaphase chromosomes were stained with silver following a pretreatment with a heated alkaline solution. The most conspicuous feature of the stained metaphases was the omission of silver staining in the secondary constrictions of chromosomes 1,9 and 16, and on the distal Yq. Our evidence indicates that the negative silver binding is due to the preferential removal or alteration of non-histone proteins associated with these regions. The cytochemical significance of these findings is discussed.

PubMed Disclaimer

References

    1. Experientia. 1975 Feb 15;31(2):260-2 - PubMed
    1. Chromosoma. 1974;49(2):161-71 - PubMed
    1. Stain Technol. 1965 Nov;40(6):333-8 - PubMed
    1. Chromosoma. 1972;37(2):117-30 - PubMed
    1. Experientia. 1974 Nov 15;30(11):1364-6 - PubMed