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. 1967 Jul 7;157(3784):75-6.
doi: 10.1126/science.157.3784.75.

Benzpyrene hydroxylase induction by polycyclic hydrocarbons in hamster embryonic cells grown in vitro

L J Alfred, H V Gelboin

Benzpyrene hydroxylase induction by polycyclic hydrocarbons in hamster embryonic cells grown in vitro

L J Alfred et al. Science. .

Abstract

Treatment of hamster embryonic cells with 1,2-benzanthracene for 4 to 48 hours induced a three- to tenfold increase in the activity of benzpyrene hydroxylase. That the increase in enzyme activity was completely prevented by puromycin suggested an induction of enzyme synthesis.

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