[Blood regeneration after blood substitution with dextran 60 or hydroxyethyl starch of an identical volume]

Abstract

Male rats of the Wistar strain survived an isovolaemic blood volume replacement down to a haematocrit value of 20% using commercial dextran 60 or hydroxyethyl starch. No significant changes of the blood volume have been observed. 14 days after treatment, the blood values were found to be practically within the normal range. As early as 3 days after the blood exchange, a significant increase in reticulocytes has been noted which reached its maximum on the 7th day. In both series the blood regeneration was identical.