Reconstruction of intact gamma-globulin from S-sulfonated gamma-globulin in vivo
- PMID: 60334
- DOI: 10.1093/oxfordjournals.jbchem.a131192
Reconstruction of intact gamma-globulin from S-sulfonated gamma-globulin in vivo
Abstract
The conversion of the S-surfonate group in a peptide to a disulfide bond has been observed in vitro. This paper reports that the conversion of this group in human S-sulfonated gamma-globulin (S-GG) appeared to occur in vivo judging from the change in molecular weight of S-GG observed in the presence of sodium dodecyl sulfate (SDS) and the restoration of hemolytic activity.
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