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. 1967 Apr;103(1):202-6.
doi: 10.1042/bj1030202.

The biosynthesis of dicoumarol

D M Bellis, M S Spring, J R Stoker

The biosynthesis of dicoumarol

D M Bellis et al. Biochem J. 1967 Apr.

Abstract

Micro-organisms have been isolated that can utilize o-coumaric acid as a sole carbon source with the subsequent production of 4-hydroxycoumarin and dicoumarol. One of these organisms, Penicillium jenseni, has been used to examine the biosynthesis of dicoumarol. Certain thermophilic fungi have also been found that can convert o-coumaric acid into dicoumarol.

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