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. 1967 Jul;50(6):1751-64.
doi: 10.1085/jgp.50.6.1751.

Cation movements in the high sodium erythrocyte of the cat

R I Sha'afi, W R Lieb

Cation movements in the high sodium erythrocyte of the cat

R I Sha'afi et al. J Gen Physiol. 1967 Jul.

Abstract

The uptake of (42)K and (24)Na by cat erythrocytes was investigated. Under steady-state conditions, the nontransient component of (42)K influx was found to be 0.18 +/- 0.01 meq/liter RBC/hr and insensitive to ouabain (100 microM); the corresponding value for (24)Na was 17 +/- meq/liter RBC/hr. A study was made of the effects of anions upon cation movements in these and other mammalian red cells. Iodide was found to inhibit markedly (>50%) Na inward movements in cat and dog but not in the other erythrocytes. An increase (15-30%) in K uptake in the presence of iodide was noted in all the mammalian cells studied.

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