Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1967 May;2(3):343-50.

Factors influencing the immune response. II. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intraperitoneal injection of bovine serum albumin in rabbits

R N Pinckard, D M Weir, W H McBride

Factors influencing the immune response. II. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intraperitoneal injection of bovine serum albumin in rabbits

R N Pinckard et al. Clin Exp Immunol. 1967 May.

Abstract

The injection of Corynebacterium parvum at the same time as centrifuged bovine albumin has been shown not to have the adjuvant effect found when C. parvum is injected 6 days before. The implication of this is discussed and related to mechanisms of antibody synthesis.

Whereas particulate alum-precipitated centrifuged bovine albumin was shown to be more effective than centrifuged bovine albumin in inducing primary antibody stimulation, the reverse was true for secondary stimulation by the intraperitoneal route.

PubMed Disclaimer

References

    1. Immunology. 1966 Nov;11(5):421-6 - PubMed
    1. J Theor Biol. 1963 Sep;5(2):321-39 - PubMed
    1. Biochemistry. 1964 Jul;3:996-1008 - PubMed
    1. Ann Inst Pasteur (Paris). 1964 May;106:771-7 - PubMed
    1. J Exp Med. 1966 Sep 1;124(3):417-29 - PubMed

Substances

LinkOut - more resources