Studies on haem alpha-methenyl oxygenase. Isomeric structure of formylbiliverdin, a possible precursor of biliverdin
- PMID: 6035512
- PMCID: PMC1270541
- DOI: 10.1042/bj1040020
Studies on haem alpha-methenyl oxygenase. Isomeric structure of formylbiliverdin, a possible precursor of biliverdin
Abstract
1. The enzyme from guinea-pig liver that degrades pyridine-haemochromogen into formylbiliverdin, a possible precursor of biliverdin, breaks the porphyrin ring exclusively at the alpha-methene bridge. The enzyme is therefore appropriately named haem alpha-methenyl oxygenase. 2. It is deduced that this enzyme plays an essential role in haemoglobin catabolism in vivo.
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